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Ankylosing Spondylitis

Overview

Ankylosing Spondylitis is a chronic inflammatory disease of the spine and sacroiliac joints of unknown etiology. It is more common in men than women. When it affects the spine, it causes the spine to be less flexible and results in hunching over time.

Signs and Symptoms

Low back pain worse at night, Stiffness of the back in the morning upon waking up, Pain radiates from sacroiliac joints to the buttocks and hips, Progressive loss of spinal movements

Common Causes

Unknown causes

Risk Factors

Age, Male gender, Genetic factors (HLA-B27 gene), Environmental factors

Investigation Techniques

Clinical examination of the spine and joints, MRI scan, X-ray of the affected joints, Full blood count

Treatment and Prevention

Physiotherapy, NSAIDs, TNF alpha-blockers, Local steroid injections, Surgery

Generics

Beta-Cyclodextrin
Celecoxib
Dexketoprofen
Diclofenac
Etanercept
Etoricoxib
Flurbiprofen Oral
Flurbiprofen Patch
Hydroxychloroquine
Ibuprofen
Indomethacin
Ketoprofen
Ketorolac
Leflunomide
Meloxicam
Naproxen Sodium
Piroxicam
Sulfasalazine
Authorship
Written By
Dr Sri Viknarajan
MD (Universiti Hasanuddin, Indonesia)
Reviewed By
Dr Nur Syuhada binti Zulkifli
MD, Universiti Kebangsaan Malaysia (UKM)
Information Updated on : Wed Feb 12 2020 16:04:04 GMT+0800 (Malaysia Time)
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