Chronic Kidney Disease

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University
Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Chronic Kidney Disease

Chronic kidney disease happens when kidneys are damaged and fails to perform its normal functions, such as filtering our waste products, produce erythropoietin and regulate blood pressure. It happens gradually and usually shows no symptoms in the early stages.

Signs and Symptoms of Chronic Kidney Disease

Changes in frequency of urination, Swelling of feet and ankles, Nausea and vomiting, Loss of appetite, High blood pressure, Shortness of breath, Chest pain, Dry and itchy skin, Muscle cramps, Weakness, Fatigue, Confusion and drowsiness

Common Causes of Chronic Kidney Disease

High blood pressure, Type 1 and 2 diabetes, Recurrent pyelonephritis (kidney infection), Polycystic kidney disease, Glomerulonephritis, Interstitial nephritis, Renal aretery stenosis, Vesicoureteral reflux, Longstanding kidney stones that obstructs urinary flow, Nephrotoxic medications, Heavy metal poisoning

Risk Factors of Chronic Kidney Disease

High blood pressure, Type 1 and 2 diabetes, Obesity, Family history of kidney disease, Increasing age, Smoking, Drug abuse or overdose, Structural abnormalities in kidney, Cardiovascular disease

Investigation Techniques for Chronic Kidney Disease

Medical history, Physical examination, Blood tests to look for changes in the estimated gloverular filtration rate (eGFR) and levels of creatinine and urea, Urine tests, Ultrasound of the kidneys to examine kidney structure, Kidney biopsy

Treatment and Prevention of Chronic Kidney Disease

Lifestyle changes, Treatment of underlying cause, High blood pressure medications, Cholesterol-lowering medications, Diuretics, Calcium and vitamin D supplements, Erythropoietin supplements, Low protein diet, Fluid restriction, Hemodialysis and peritoneal dialysis, Kidney transplant

Available Chronic Kidney Disease Medicines

No medicines currently available for this condition.

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