Hodgkin’s Disease

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University

Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Hodgkin’s Disease

Hodgkin’s Disease also known as Hodgkin’s Lymphoma is a cancer of the lymphatic system which is a part of the immune system. It usually affects young adults between 20 to 40 and has a male predominance.

Signs and Symptoms of Hodgkin’s Disease

Painless and non-tender asymmetrical firm discrete and rubbery enlarged superficial lymph nodes, Fever, Pruritus, Weight loss, Night sweats, Weakness, Fatigue, Splenomegaly, Hepatomegaly

Common Causes of Hodgkin’s Disease

Genetic mutation

Risk Factors of Hodgkin’s Disease

Age, Gender, Family history of lymphoma, Previous Epstein-Barr infection

Investigation Techniques for Hodgkin’s Disease

Full blood count, Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), Serum LDH, Histological examination of lymph nodes, Chest X-ray, CT scan