Huntington's Disease

Overview

Huntington's disease is a condition causing progressive degeneration of nerve cells in the brain. It is an inherited disease and causes a wide range of symptoms that affects the cognitive, coordination, movement and memory.

Signs and Symptoms

Personality changes, Mood swings, Depression, Forgetfulness, Impaired judgment, Unsteady gait & involuntary movements (chorea), Slurred speech, Difficulty in swallowing & significant weight loss

Common Causes

Gene Mutation

Risk Factors

Family History

Investigation Techniques

CAG repeat testing, MRI or CT scan, Genetic study, Physical examination

Treatment and Prevention

Tetrabenazine, Antipsychotic drugs, Other medications that may help suppress chorea include amantadine, Antidepressants, Mood-stabilizing drugs, Psychotherapy, Speech therapy, Physical therapy, Occupational therapy

Psychological Issues

Depression, Stress

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Information Updated on : Wed Feb 12 2020 16:04:04 GMT+0800 (Malaysia Time)

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