Huntington’s Disease

Medical Review

Written by: Dr. Von Chiao Wen Doctor of Medicine (MD), N.I. Pirogov Russian National Research Medical University

Reviewed by: Dr. Lee Chin Meng Doctor of Medicine (MD), Manipal Academy of Higher Education (MAHE)

Overview of Huntington’s Disease

Huntington’s disease is a condition causing progressive degeneration of nerve cells in the brain. It is an inherited disease and causes a wide range of symptoms that affects the cognitive, coordination, movement and memory.

Signs and Symptoms of Huntington’s Disease

Personality changes, Mood swings, Depression, Forgetfulness, Impaired judgment, Unsteady gait & involuntary movements (chorea), Slurred speech, Difficulty in swallowing & significant weight loss

Common Causes of Huntington’s Disease

Gene Mutation

Risk Factors of Huntington’s Disease

Family History

Investigation Techniques for Huntington’s Disease

CAG repeat testing, MRI or CT scan, Genetic study, Physical examination

Treatment and Prevention of Huntington’s Disease

Tetrabenazine, Antipsychotic drugs, Other medications that may help suppress chorea include amantadine, Antidepressants, Mood-stabilizing drugs, Psychotherapy, Speech therapy, Physical therapy, Occupational therapy

Available Huntington’s Disease Medicines

No medicines currently available for this condition.