Wilson’s Disease

Wilson disease is a rare condition which is commonly due to genetic factor. It is an autosomal recessive type of inheritance which affects the copper metabolism where there will be excessive amount of copper in the body.

Fatigue, Lack of appetite, Abdominal pain, Jaundice, Golden-brown eye discoloration (Kayser-Fleischer rings), Ascites & edema, Problems with speech or swallowing or physical coordination, Uncontrolled movements or muscle stiffness

Genetic factor

Family history with same disease

Liver function test, 24 Hour urine copper, Serum copper, Serum ceruloplasmin, Slit lamp examination, Liver biopsy

Diet : Avoid foods with high copper content, Lifelong Penicillamine, Screen siblings, Liver transplantation