Betamethasone

Information About Betamethasone

Uses of Betamethasone

Betamethasone is used for the treatment of allergic conditions, asthma, cancer, eye disorders, nephrotic syndrome, oral lichen planus, rheumatic disorder, severe allergic reactions, and skin disorder

How Betamethasone Works

Betamethasone is a corticosteroid which has anti-inflammatory property. It binds to glucocorticoid receptors and reduces the formation, activity, and release of prostaglandins, leukotrienes, and other inflammatory mediators.

Side Effects of Betamethasone

Cushingoid facies, Hirsutism, Weight gain, Increased appetite, hyperhidrosis, Opportunistic infection, osteoporosis, Proximal myopathy, Sodium and water retention, Menstrual irregularity

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Betamethasone Related Warnings

Alcohol Not Advisable

Corticosteroids may cause dry skin. Drinking alcohol may aggravate its side effects.

Pregnancy Not Safe

There is evidence of teratogenicity in animal studies. However, there is no evidence in human studies

Lactation Limited Data

Betamethasone is probably safe to use during lactation. Limited human data and animal studies suggest that Betamethasone does not represent a significant risk to nursing infants. However, Betamethasone needs to be taken with caution.

Driving Generally Safe

Betamethasone usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

The effect of Betamethasone on the kidney is not known. However, it is safer to use with caution and consult a doctor before using this medication.

Liver Limited Data

Long term usage of Betamethasone may cause liver damage such as hepatic enlargement and steatosis. It also may exacerbate nonalcoholic steatohepatitis chronic viral hepatitis