Chlorzoxazone

Information About Chlorzoxazone

Uses of Chlorzoxazone

Chlorzoxazone is commonly used to treat pain due to muscle spasm

How Chlorzoxazone Works

Chlorzoxazone is a centrally acting skeletal muscle relaxant. It works by inhibiting the polysynaptic reflex arcs in the spinal cord and subcortical areas of the brain thus reducing the skeletal muscle spasm and pain.

Side Effects of Chlorzoxazone

Drowsiness, Dizziness, Headache, Malaise, Nausea, Vomiting, Loss of appetite, Jaundice, Skin rash,

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Chlorzoxazone Related Warnings

Alcohol Not Advisable

Chlorzoxazone and alcohol consumption may worsen the effects on the central nervous system as their adverse reactions may be compounded.

Pregnancy Limited Data

There is no relevant animal data and very limited human data available. Based on the data that is available, Chlorzoxazone uses may not cause teratogenicity.

Lactation Limited Data

No human data to study the effects during lactation as well but it is assumed to be compatible during lactation and close monitoring is advisable.

Driving Not advisable

It is not advisable to drive when taking Chlorzoxazone due to its potential side effects such as drowsiness and dizziness which can affect the ability to drive and concentrate.

Kidney Safe If Prescribed

No dosage adjustment is needed for people with renal impairment despite it being excreted via urine.

Liver Limited Data

Chlorzoxazone is contraindicated to be used in a patient with hepatic impairment due to its potential toxicity.