Clotrimazole

Information About Clotrimazole

Uses of Clotrimazole

Clotrimazole is commonly used in the treatment of fungal infections and severe fungal infections.

How Clotrimazole Works

Clotrimazole is an antifungal that is able to bind to the phospholipids in the fungal cell membrane. This is done by altering the permeability of the cell wall, which eventually leads to the loss of important intracellular elements, leading to fungal cell death.

Side Effects of Clotrimazole

Gastrointestinal disturbance, Nausea, Vomiting, Diarrhea , Dysuria, Allergic reactions, Stinging sensation, Erythema, Local irritation, Mental depression, Elevation of liver enzymes

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Clotrimazole Related Warnings

Alcohol Safe

It is safe to consume alcohol with Clotrimazole. Consuming clotrimazole with alcohol will not interfere with the way the medication works.

Pregnancy Not Safe

Topical Clotrimazole can be used during pregnancy. Animal reproduction studies do not demonstrate adverse effects on fetus with the use of topical Clotrimazole, and there are no adequate studies in pregnant women. However, animal reproduction studies do demonstrate adverse effects on the fetus when it is taken orally. This medication should only be used after the benefits and risks have been weighed properly. Please consult the doctor before consuming Clotrimazole.

Lactation Limited Data

Clotrimazole is shown to be excreted during lactation in animal studies. Because of its potential adverse drug effects on infants, patients have to decide whether to discontinue Clotrimazole or to stop breastfeeding. This medication should only be used after the benefits and risks have been weighed properly. Please consult the doctor before use.

Driving Generally Safe

Clotrimazole usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Clotrimazole can be used in patients with kidney issues.

Liver Limited Data

Clotrimazole should be used with caution in patients with liver issues. Dose adjustment of Clotrimazole may be needed. Please consult the doctor.