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Prednisolone is commonly used to treat allergic conditions, arthritis, asthma, cancer, eye disorders, nephrotic syndrome, rheumatic disorder, severe allergic reactions, skin disorders.
Prednisolone is a corticosteroid. It reduces inflammation by reversal of increased capillary permeability and suppresses the polymorphonuclear leukocytes migration. It also affects the lymphatic system by reducing its activity and volume.
Adrenal suppresion, Fluid and electrolyte disturbances, hyperglycemia, Peptic ulcer, Glaucoma, Depression, Weight gain, Arrest of growth.
It is unsafe to consume alcohol with Prednisolone. Taking Prednisolone with alcohol may enhance the gastric mucosal irritation.
Prednisolone may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. Sorticosteroids should only be prescribed when the benefits to the mother and child outweigh the risks. Patients with pre-eclampsia or fluid retention require close monitoring. Please consult your doctor.
Doses of up to 40mg daily of prednisolone are unlikely to cause systemic effects in the infant. Infants of mothers receiving 40mg or more daily should be monitored for signs of adrenal suppression but the benefits of breast-feeding are likely to outweigh any theoretical risk.
Prednisolone usually does not affect the ability to drive. Do not drive unless you are feeling well.
Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed. Please consult your doctor for confirmation.
The effect of corticosteroids may be enhanced in patients with chronic liver disease with impaired hepatic function.