Pancreatic Enzyme Deficiency

Overview

Pancreatic Enzyme Deficiency is a condition characterised by deficiency in exocrine pancreatic enzyme which leads to inability to digest food and malabsorption. The main enzymes secreted are amylase, protease and lipase

Signs and Symptoms

Steatorrhea, Weight loss, Tiredness, Gas, Cramps, Bloating, Pain in the center of the stomach that radiates to the back, Loss of muscle, Signs of vitamin deficiency, such as brittle nails/ hair loss/and skin problems

Common Causes

Pancreatic cancer, Surgical removal of the pancreas, Obstructions of the pancreatic duct, Celiac disease, Crohn's disease, Autoimmune pancreatitis, Diabetes

Risk Factors

Chronic pancreatitis, Chronic alcohol abuse

Investigation Techniques

Blood tests, Stool tests, Fat absorption tests, D-xylose test, Bile salt absorption test, Pancreatic Function Tests, Abdominal Imaging

Treatment and Prevention

Pancreatic enzyme replacement therapy, Vitamin supplementation, Lifestyle modifications