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Qtern 5/10mg Tablet 28s

RM 305.07

RM 228.80

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28s

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28s

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Product Overview

Introduction of Qtern 5/10mg Tablet 28s

Irritation in the throat, trouble swallowing, and fungal infections in the mouth or throat are the most frequent adverse effects. If you have these symptoms, do not stop taking your medication; instead, see your doctor. After using your inhaler, rinse your mouth and throat with water or brush your teeth to help avoid these symptoms. Other, less common, but potentially dangerous adverse effects exist. If you are concerned about them, speak with your doctor.

How To Use Qtern 5/10mg Tablet 28s

This medicine is for oral use only. Swallow this medication as a whole with water. Do not chew, crush or break it. It is better to take this medication at a fixed time each day if it is indicated for everyday use.

Brands

AstraZeneca

Active Ingredient

dapagliflozin saxagliptin

Manufactured by

AstraZeneca Pharmaceuticals LP

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Take this medication at the dosage and frequency prescribed by your doctor. Swallow it down as a whole. Do not chew, crush or break it down. Qtern 5mg/10mg Tablet can be taken with or without food, but it is best taken at a fixed time.

The most common side effects of this medication are upper respiratory tract and urinary tract infection. Drinking plenty of water and practising good health will help you prevent this from happening. It can also cause dizziness and sleepiness, so do not drive or do something that needs a mental concentration until you know how this medication affects you.

Nausea, Constipation, Thirst, Dry mouth, Back pain, Dizziness, Urticaria, Hypoglycemia, Dysuria, Rash, Vaginitis/balanitis, Urinary Tract Infection

Headache, Fatigue, Dizziness, Heartburn, Peripheral oedema, Muscle/Joint ache, Hypoglycaemia, Hypertriglyceridaemia, Erectile dysfunction, Allergic reactions, Pancreatitis

Warning Precautions

Alcohol Warning (Not Advisable)

There is no known interaction of Qtern 5/10mg Tablet 28s with alcohol.The interaction of alcohol and Qtern 5/10mg Tablet 28s have not been studied specifically. Thus, it is not advisable to consume alcohol with Qtern 5/10mg Tablet 28s as risks cannot be excluded.

Pregnancy Warning (Not Safe)

Qtern 5/10mg Tablet 28s may be unsafe to use during pregnancy. Animal reproduction studies have shown adverse effects on the fetus. However, there are limited well-controlled human studies. The benefits from the use of Qtern 5/10mg Tablet 28s in pregnant women may be acceptable despite the risk. Please consult your doctor. Animal studies have shown reproductive toxicities at high doses but there are no data on the use of Qtern 5/10mg Tablet 28s in pregnant women. Thus, it is not advisable to be used unless clearly indicated. Please consult your doctor.

Breastfeeding Warning (Not Advisable)

Qtern 5/10mg Tablet 28s is contraindicated during lactation. Animal studies have shown excretion of Qtern 5/10mg Tablet 28s in milk. Excretion of Qtern 5/10mg Tablet 28s has been found in animal milk but it is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.

Driving Warning (Generally Safe)

Qtern 5/10mg Tablet 28s usually does not affect the ability to drive. Do not drive unless you are feeling well.Qtern 5/10mg Tablet 28s usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (High Risk)

Qtern 5/10mg Tablet 28s is contraindicated in patients with moderate to severe renal impairment and patients on dialysis. This is because the glycemic efficacy of the drug depends on renal function. Dose adjustment of Qtern 5/10mg Tablet 28s and monitoring of renal function is necessary. Please consult your doctor. Dose adjustment is needed in patients with moderate to severe kidney impairment. Qtern 5/10mg Tablet 28s is contraindicated in patients with end-stage kidney disease on hemodialysis.

Liver Warning (Use With Care)

Qtern 5/10mg Tablet 28s should be used with caution in patients with severe liver impairment. Dose adjustment of Qtern 5/10mg Tablet 28s may be needed. Please consult your doctor.Caution use has to be practised in patients with moderate liver impairment. Qtern 5/10mg Tablet 28s is contraindicated in patients with severe liver impairment.

Quick Tips

Take it every day at the same time to make you remember to take it. Qtern 5mg/10mg Tablet can cause hypoglycemia (low blood sugar) when used with other antidiabetic medicines, alcohol or if you delay or skip a meal.
Always take some sugary food or fruit juice with you if you experience signs of hypoglycemia such as cold sweats, cool pale skin, tremor and anxiety.
It can cause your body to lose too much fluid (dehydration) or urinate more often.
Drink plenty of water to keep yourself hydrated.
It may cause genital fungal and/or urinary tract infections (UTIs) in both females and males, so do practice good hygiene.
Your doctor will routinely monitor your kidney function before and during treatment.

FAQ

Does Qtern 5/10mg Tablet 28s cause hypoglycaemia?

Qtern 5/10mg Tablet 28s does not usually cause hypoglycaemia (low blood sugar) when taken on its own. However, it may occur when other glucose controlling medications are added to your therapy due to suboptimal control of your blood glucose levels.

Why does Qtern 5/10mg Tablet 28s increase the risk of developing genital and urinary tract infections?

Due to the way in which Qtern 5/10mg Tablet 28s works to lower your blood glucose levels, Qtern 5/10mg Tablet 28s provides a favourable environment for fungus to thrive and grow thereby resulting in genital infections developing. Qtern 5/10mg Tablet 28s also removes excess glucose by increasing the excretion of glucose into your urine which may lead to urinary tract infections. Therefore, it is advised that you increase your fluid intake and maintain good personal hygiene.

Does Qtern 5/10mg Tablet 28s cause weight gain?

No, Qtern 5/10mg Tablet 28s does not commonly cause weight gain.

References

1. Qtern (dapagliflozin or saxagliptin) [FDA Label]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2017. [Accessed 21 Feb. 2020] (online)

2. Qtern (saxagliptin/dapagliflozin) [Package Leaflet]. Södertälje, Sweden: AstraZeneca AB; 2019. [Accessed 21 Feb. 2020] (online)

3. Qtern (saxagliptin/dapagliflozin) [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2017 [revised Jan. 2020]. [Accessed 21 Feb. 2020] (online)

4. BNF 73

5. Empagliflozin: medicine used to treat type 2 diabetes, National Health Services

6. Unnikrishnan AG, Kalra S, Purandare V, Vasnawala H. Genital Infections with Sodium Glucose Cotransporter-2 Inhibitors: Occurrence and Management in Patients with Type 2 Diabetes Mellitus. Indian J Endocrinol Metab. 2018;22(6):837-842. doi:10.4103/ijem.IJEM_159_17

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Disclaimer

Information last updated on: Tue Oct 29 2024 02:15:19 GMT+0800 (Malaysia Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Qtern 5/10mg Tablet 28s is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.

Qtern 5/10mg Tablet 28s is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.

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Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ming Jer Gan

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