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Mupirocin is commonly used to treat severe bacterial infections.
Mupirocin works by binding to isoleucyl transfer ribonucleic acid (tRNA)-synthetase and thus inhibiting the synthesis of protein by the bacteria. It is bacteriostatic at minimal inhibitory concentrations and bactericidal at higher concentrations.
Skin irritation, Rash, Dry skin, Erythema, Cellulitis, Secondary wound infection, Swelling, Urticaria, Nausea, Headache, Burning and tearing of eyes, Dry mouth
It is safe to drink alcohol while using mupirocin.
Animal studies did not demonstrate a risk to the fetus and there are inadequate human studies in pregnant women. Mupirocin should only be used if the benefits outweigh the potential risks to the fetus.
It is not known whether mupirocin is excreted in breast milk, therefore care should be practised if the usage during breastfeeding is indicated.
Mupirocin usually does not affect the ability to drive. Do not drive unless you are feeling well.
Mupirocin should be used with caution in patients with kidney disease. However, dosage adjustment is unnecessary.
It is safe to use mupirocin in patients with liver impairment. Adjustment of dosage is not required.
