Sennosides

Information About Sennosides

Uses of Sennosides

Sennosides is commonly used to treat constipation

How Sennosides Works

Sennosides is a laxative which is able to increase the prostaglandin level in the gut, leading to restriction of water reabsorption due to decrease in aquaporin 3 production. This will produce a laxative effect that helps in patients with constipation.

Side Effects of Sennosides

Mild abdominal discomfort, Diarrhea, Hypokalaemia, Atonic colon, Reversible melanosis coli, Yellowish-brown urine/Red urine

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Sennosides Related Warnings

Alcohol Safe

There is no known interaction between alcohol and Sennosides when used concomitantly.

Pregnancy Not Safe

Components of Sennosides are found to have toxicities in experimental studies. Thus, it is not advisable to be used during pregnancy.

Lactation Limited Data

There are limited data showing the excretion of metabolites in human breast milk. Thus, it is not advisable to be used during breastfeeding.

Driving Generally Safe

There are no studies about the effect of Sennosides on the ability to drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Sennosides is safe to be used in patients with kidney impairment.

Liver Limited Data

Sennosides is safe to be used in patients with liver impairment.