Dengue vaccine: What everyone should know?

Vaccination is a key weapon in controlling this disease, and a recently produced dengue vaccine appears to provide promise of protection. With the rising number of dengue cases in Malaysia, this is a step forward in the medical world, as we have all hoped for a cure for dengue fever.

Can you tell me more about the new dengue vaccine?

Qdenga is a new dengue vaccine aimed at preventing dengue fever, which is common in tropical and subtropical countries. Qdenga is particularly important for dengue-endemic countries where the disease is prevalent. It is intended to offer immunity against all four dengue virus serotypes, providing another level of protection.

What is the rate of safety and effectiveness?

It is the first and the only dengue vaccine that has been approved in Malaysia. The effectiveness of the vaccine is particularly high in individuals with prior dengue infection. This vaccine ensures an 80.9% rate of effectiveness towards fighting dengue disease.

Individuals aged four and above can receive this vaccine in two doses within a three-month interval. This high rate of effectiveness can ensure that Qdenga is completely safe and reliable. Plus, the Qdenga vaccine does not have deadly side effects, unlike the other types of dengue vaccines.

Does it have any side effects?

Qdenga, like other vaccinations, has side effects, but none have been recognised as serious since it was approved for use. Simply a mild side effect showing that the vaccine is working in your body. 

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Common side effects

• Pain and swelling around the injection site

  

• Fever 
• Headache
• Fatigue
• Joint ache

These side effects usually go away on their own within a few days.

Rare and Serious Side Effects

There are some cases where people may encounter more serious side effects. These may include:

• Serious allergic responses 
• Severe headache
• Persistent vomiting
• Chest pain

These major side effects occur rarely but should be thoroughly checked. Anyone who shows these symptoms should seek quick medical assistance.

What should we do for dengue prevention?

First, refrain from panicking and remain calm. If you experience any of these side effects, please observe them for a few days and seek treatment immediately if they remain.

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Comparing to Dengvaxia

What's the Difference?

Dengvaxia was the first dengue vaccine to be made available. Screening for previous dengue infection is required before administering Dengvaxia. It has been reported that Dengvaxia is a deadly case after vaccination plus it is not approved in Malaysia.

Is it better or worse?

Qdenga seems to have a wider range of uses and is safer for people who have had dengue before and people who have never had dengue before. Qdenga is effective for individuals with and without prior dengue infection. It is the only vaccine that has been approved in Malaysia considering how safe it is.

In conclusion

With a high rate of success and a usually good safety profile, Qdenga is a big step forward in preventing dengue. It might have some minor side effects, but they are usually not too bad. Because it works better than Dengvaxia, it could help lower the number of people who get dengue fever around the world. Qdenga plays a crucial role in dengue prevention and reducing the burden of the disease.

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References

- “Dengue – Malaysian Society of Infectious Diseases & Chemotherapy.” Guidelines for Adult Immunisation, https://adultimmunisation.msidc.my/dengue/ . Accessed 17 May 2024.

- “Dengue Vaccine - Singapore.” HealthHub, 10 January 2023, https://www.healthhub.sg/a-z/medications/dengue%20vaccine . Accessed 17 May 2024.

- “Dengue and severe dengue.” World Health Organization (WHO), 23 April 2024, https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue . Accessed 16 May 2024. 

- “Dengue Fever and the New Dengue Vaccine.” Samitivej Hospital in Bangkok, Thailand, https://www.samitivejhospitals.com/article/detail/dengue-fever-and-the-new-dengue-vaccine . Accessed 16 May 2024.

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