Alkalinizing Agent

Overview

Alkalinizing agents are substances used to manage conditions associated with low pH levels or acidosis. Example of conditions or disorders that needs alkalinizing agents are gastrointestinal disorders such as peptic ulcer disease and gastric reflux disease, gallstones, renal tubular acidosis, renal calculi, urinary tract infections, metabolic acidosis, diabetic ketoacidosis, gout and any other acidic condition in the body. Some of the common alkalinizing agents that used to treat these conditions include sodium bicarbonate, sodium citrate, sodium lactate, potassium citrate, calcium bicarbonate, and calcium acetate. These agents are mostly administered intravenously. Some can be given orally as well depending on the condition being treated. Alkalinizing agents work by lowering the hydrogen electrolyte levels in the plasma and extracellular fluid, hence increasing the bicarbonate levels. This causes an increase in the pH levels in the body. Before the administration of alkalizing agents, it is crucial to monitor the patient's blood gases levels, serum electrolyte levels, and oxygen saturation.