Rabies is a disease caused by Rhabdovirus which affects the nervous system tissues primarily. The virus is transmitted frequently passed on through saliva through bites or licks on abrasions or intact mucous membranes. Dogs or bats frequently transmit it. The presentation in the beginning stages is very unspecific as they begin with fever and paraesthesia around the region of the bite. Then after some time, it causes the patient to be more anxious and develop hydrophobia. Delusions or hallucinations may develop alongside mania. Diagnosis can be made upon a thorough history and physical examination with the presentations of the patient. However, rapid immune fluorescent techniques can detect the antigen in skin biopsy. Treatment for rabies is often supportive and symptomatic treatment and look out for cardiac or respiratory failure. Nutrition and fluids should be given intravenously.