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Adapalene is commonly used to treat acne.
Adapalene is a retinoid-like compound which has anti-inflammatory action. Adapalene works by normalising the differentiation of follicular epithelial cells resulting in decreased acne. It binds to the specific retinoic acid nuclear formation.
Stinging and burning sensation, Skin discoloration, Sunburn, Skin irritation, Scaling and erythema, Pruritus, Rash, Eczema, Acne flare, Dermatitis
It is unsafe to apply alcohol with Adapalene. Using Adapalene with alcohol may have additive irritant effects. You may experience skin irritation, stinging and burning sensation and sunburn.
Adapalene may be unsafe to use during pregnancy. Animal studies have shown negative effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Adapalene is probably safe to use during lactation, however, avoid application to the chest to prevent contact exposure of the infant. No human data suggests that Adapalene does not represent a significant risk to the baby.
Adapalene usually does not affect the ability to drive. Do not drive unless you are feeling well.
Adapalene can be used in patients with kidney disease since its absorption is minimal.
Adapalene should be used with caution in patients with liver disease because it was excreted via bile. Dose adjustment may be needed. Please consult your doctor.
