Albendazole

Information About Albendazole

Uses of Albendazole

Albendazole is commonly used in the treatment of diarrhea, filariasis, hepatic amoebiasis, intestinal amoebiasis, liver abscesses, periodontitis, schistosoma infections and worm infections.

How Albendazole Works

Albendazole is an antihelminthic which can inhibit the formation of microtubule of the parasite. As a result, this will cause reduced glucose uptake and absorptive function as well as exhausting glycogen storage in the parasites, subsequently leading to parasite death.

Side Effects of Albendazole

Blurred vision, Abdominal pain, Nausea, Vomiting, Diarrhea, Fever, Headache, Dizziness, Convulsion, Rash, Sleepiness

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Albendazole Related Warnings

Alcohol Not Advisable

There are no academic reports on the interaction between albendazole and alcohol. However, since alcohol consumption increases the risk for liver problems and this medication may also cause liver problems, it is advisable to restrict taking alcoholic drinks.

Pregnancy Not Safe

There are adverse effects on the fetus as shown in animal studies, however, there are no sufficient and well-controlled data from human studies. In pregnancy, albendazole should only be used if the benefits outweigh the risks to the fetus. It is best to avoid using this medication during pregnancy.

Lactation Limited Data

Animal studies have shown that it is excreted in animal milk. It is also excreted in human milk. It is important to take caution before using this medication during lactation.

Driving Generally Safe

Albendazole usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

There is no study on the pharmacokinetics of albendazole in patients with renal problems, however, caution must be taken since it may cause acute renal failure.

Liver Use With Care

It is good to take caution in patients with liver disease as albendazole may cause elevation of hepatic enzyme, hepatitis, and acute liver failure. There is also an increased risk of bone marrow suppression in such patients.