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Aprepitant

Information About Aprepitant

Uses of Aprepitant

Aprepitant is commonly used to treat nausea, nausea and vomiting due to chemotherapy, vomiting

How Aprepitant Works

Aprepitant is a SP neurokinin 1 (NK1) receptor antagonist. Which means it is an antiemetic that works by making the receptors more selective towards NK1 compared to other enzymes, ion channel, transporter or receptor that may induce nausea.

Side Effects of Aprepitant

Hiccups, Dizziness, Fatigueness, Constipation, Headache, Loss of appetite

Information Updated on : Wed Jul 17 2024 10:48:35 GMT+0800 (Malaysia Time)

Available Medicine for Aprepitant

Aprepitant Related Warnings

Alcohol Safe

No available data on reactions between Aprepitant and alcohol. Small amount of alcohol, however, does not appear to affect the effectivitiy and safety of Aprepitant

Pregnancy Not Safe

Aprepitant may be unsafe to use during pregnancy. Since there are limited human studies, it is inconclusive. It can be used only if potential benefit justifies the potential risk to the mother and fetus.

Lactation Limited Data

In animal study, Aprepitant is excreted into the milk of rats. However, there is no data available on human milk. Depending on other drugs consumed by the mother and its interaction with Aprepitant thus its excretion, it will be described upon careful consideration.

Driving Not advisable

Do not drive unless you are feeling well. Aprepitant may cause side effects such as dizziness, headaches, fatigueness, all of which may affect your ability to concentrate and drive.

Kidney Safe If Prescribed

Aprepitant may be used in patients with kidney disease. Dosage adjustment is not necessary. Please consult your doctor.

Liver Use With Care

Aprepitant is safe in patients with liver disease. Dosage adjustment is not necessary in mild to moderate hepatic insufficiency patients. Patients with severe hepatic insufficiency however have limited data. Hence, please consult your doctor.

Frequently Asked Questions on Aprepitant

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