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Atazanavir is commonly used to treat hiv infection
Atazanavir works by inhibiting HIV-1 protease enzyme which functions to cleave Gag-Pol polyprotein. This results in the production of immature and non-infectious viral particles which are non-functioning.
Jaundice, Dizziness, Headache, Insomnia, Fatigue, Skin rash, Breast enlargement, Muscle weakness, Diabetes mellitus
There is no adequate data to suggest any risk or interaction between Atazanavir and alcohol when consumed together. It is thought to be safe to consume alcohol with Atazanavir.
Animal studies and pregnant human meta-analysis suggest Atazanavir is safe to be used during pregnancy as no fetal malformation detected. Caution should still be taken as risk such as preterm delivery may increase with Atazanavir treatment.
Atazanavir has been traced in human breastmilk and may cause side effects to the newborn infant. It is recommended not to breastfeed the baby while on this treatment.
It is not advisable for patient taking Atazanavir to drive after consuming the medicine due to its potential side effects such as dizziness and headache which can affect the ability to concentrate and drive.
Renal impairment including chronic kidney disease and granulomatous interstitial nephritis has been reported. It is not advisable to be used in a patient with End-Stage Renal Disease and dialysis patient.
It is not recommended to be used in severe hepatic impairment patient. Atazanavir may cause hepatitis and elevated liver enzymes thus the need to closely monitor at baseline and during treatment.