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Bepridil is commonly used to treat chronic stable angina
Bepridil inhibits the calcium influx into vascular smooth muscle and myocardium during the depolarization phase. This results in dilated coronary vessels supplying more oxygen to the heart tissue
Dizziness, Nausea, Shortness of breath, Slow pulse, Headache, Drowsiness, Insomnia, Tremor, Sexual disturbances, Blurred vision
It is not advisable to consume alcohol when taking Bepridil as certain side effects of Bepridil such as dizziness and headache may be compounded by the effects of alcohol.
Animal studies have been shown to produce some adverse effects in terms of litter size and survival. There is no well or adequate studies on human pregnancy. Bepridil is only indicated if the benefit outweighs the risk.
It is found that there is a trace of about 1/3 of concentration of Bepridil in human breastmilk. Due to its potential toxicity and adverse effects, it is not recommended for the mother to breastfeed the infant while on this treatment.
It is not advisable to drive while taking Bepridil as it can cause side effects such as dizziness, blurred vision and headache all of which can alter the concentration and ability to drive.
Bepridil should be used with care in renal impaired patients to avoid dose toxicity. Dose adjustment may be required in this group of people.
Bepridil should be used with caution in people with hepatic impairment. Little data is obtained about the effects on liver injury and further advice should be sought before commencing the treatment with Bepridil.