Bromocriptine

Information About Bromocriptine

Uses of Bromocriptine

Bromocriptine is commonly used to treat acromegaly, female infertility, type 2 diabetes mellitus

How Bromocriptine Works

Bromocriptine is a dopamine agonist which activates postsynaptic dopamine receptor and lead to a reduction in prolactin and growth hormone secretion. It also stimulates the nigrostriatal pathways

Side Effects of Bromocriptine

Nausea, Vomiting, Drowsiness, Low blood pressure, Blocked nose, Headache, Dry mouth, Constipation, Hallucination, Delusion, Visual disturbance

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Bromocriptine Related Warnings

Alcohol Not Advisable

Alcohol is not advisable to be consumed when taking Bromocriptine as the side effects of Bromocriptine or the alcohol can be augmented due to their action on the central nervous system.

Pregnancy Maybe Safe

A large data on human pregnancy has indicated that there is no risk of teratogenicity and risk to the pregnancy itself. It is advisable to closely monitor Bromocriptine treatment in pregnant women.

Lactation Not Advisable

Bromocriptine inhibits prolactin secretion which is essential for breastmilk production. The use of Bromocriptine will inhibit breastmilk production, hence other alternatives should be sought.

Driving Not advisable

It is not advisable to drive while taking Bromocriptine due to its possible side effects to the eyes such as visual disturbance and drowsiness which can affect the concentration and ability to drive.

Kidney Safe If Prescribed

There is no need for dosage adjustment in patient with renal impairment according to the manufacturer labelling. Bromocriptine also is excreted via feces which does not involve with renal physiology.

Liver Use With Care

Due to extensive hepatic metabolism, caution should be taken when consuming Bromocriptine. Dosage adjustment may be needed according to the severity of the impairment.