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Cabergoline is commonly used to suppress high levels of prolactin in hyperprolactinemia, inhibit physiological lactation postpartum and as adjunct or monotherapy in parkinson's disease
Cabergoline is a long-acting dopamine receptor agonist that acts on D2-dopamine receptors. It suppresses prolactin secretion by stimulating dopamine release.
Abdominal discomforts such as dyspepsia and epigastric pain, Headache, Confusion, Hallucination, Constipation, Angina, Breast pain, Nausea, Postural hypotension, Syncope, Allergic reactions
A small amount of alcohol doesn't appear to reduce the safety or function of Cabergoline. However, it is not advised to take alcohol if you are feeling drowsy or dizzy after taking this medication as alcohol may exacerbate these effects.
Cabergoline does not appear to be teratogenic in animal studies, however, it has shown to exhibit maternal toxic properties. There were no adequate studies in humans but research done so far shown it may affect fertility and may cause congenital abnormality. Uses of this medication during pregnancy should be avoided unless if clearly indicated and the risk and benefit have been thoroughly evaluated.
Study in animals shows that Cabergoline is excreted in breastmilk. As there was no data of the same in humans, a mother is not advised to breast-feed while taking this medication as this medication inhibits lactation. However, lactating mothers with hyperprolactinemia who wish to breastfeed should not be treated with this medication.
As this medication could impair a person's concentration. Actions that require fast and accurate reactions such as driving and operating machines should be done with caution especially if you are not feeling well.
Long term uses of Cabergoline may cause fibrotic disorders which may involve kidney. Investigate any loin pain which may suggest renal insufficiency due to ureteral or abdominal obstruction.
Dose adjustment for Cabergoline may be needed for a patient with liver insufficiency. Higher plasma concentration has been noted in patient with severe hepatic insufficiency who receive this medication.
