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Ciprofibrate is commonly used to treat high cholesterol
Ciprofibrate acts on the nuclear transcription factor PPAR-alpha which upregulates the apolipoprotein A-1 gene and downregulate the apolipoprotein C-11 gene.
Rashes, Itchiness, Muscle weakness, Vertigo, Headache, Nausea, Vomiting, Dizziness, Somnolence, Light sensitivity
Ciprofibrate and alcohol consumption may worsen the effects on the central nervous system as their adverse reactions may be compounded.
Animal reproductive studies suggest teratogenicity and severe adverse reaction while there are no adequate human pregnant studies to suggest otherwise. It is, therefore, not advisable to be used in pregnant women without specialist recommendation.
Ciprofibrate is not known to be excreted into human breastmilk and is therefore contraindicated to be used during breastfeeding.
It is not advisable to drive when taking Ciprofibrate due to its potential side effects such as headache and dizziness which can affect the ability to drive and concentrate.
Dosage adjustment is needed in patients with mild to moderate renal impairment and is contraindicated to be used in patients with severe renal impairment.
Dosage adjustment is needed in patient with mild to moderate hepatic impairment while it is contraindicated to be used in severe hepatic impaired patients.
