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Clomiphene/clomifene is commonly used to treat female infertility caused by anovulation (ovaries cannot release an egg during menstruation).
Clomiphene/Clomifene is an oestrogen analogue. It will inhibit the effect of negative feedback receptors located on a higher level and caused the secretion of hypothalamic GnRH hormone increases, therefore, increases the pituitary FSH and LH release.
Ovarian Hyperstimulation Syndrome (OHSS), Visual disturbances, Endometriosis, Enlargement of ovary/ ovarian cyst formation, Nausea, Dizziness, Increase appetite, Weight gain, Fatigue, Vaginal dryness
Taking Clomiphene/Clomifene with alcohol may have additive effects in causing dizziness, nausea and vomiting.
Clomiphene/Clomifene is unsafe to use during pregnancy. Both animal and human studies have shown adverse effects on the fetus. This medicine is strictly prohibited in pregnancy. Use of Clomifene should be started only after pregnancy has been excluded.
Clomiphene/Clomifene has potential toxicity and not safe to use during lactation. No human data suggests that Clomifene does not represent a significant risk to the baby. Clomifene may reduce lactation in some patients.
Do not drive unless you are feeling well. Clomiphene/Clomifene may cause side effects such as visual disturbances, dizziness, or lightheadedness, all of which could affect your ability to concentrate and drive.
Clomiphene/Clomifene is excreted mainly through faeces and it is probably safe in patients with kidney disease.
Clomiphene/Clomifene is contraindicated in patients with liver disease because it metabolised in the liver; undergoes enterohepatic recirculation. Please consult your doctor.