Digoxin

Information About Digoxin

Uses of Digoxin

Digoxin is commonly used to treat arrhythmias and heart failure.

How Digoxin Works

Digoxin's inotropic activity increases the force of heart contraction. It also reduces the conductivity of the atrioventricular (AV) node by altering Na+-K+ exchange activity and increases vagal activity.

Side Effects of Digoxin

Arrhythmia, Conduction disturbances, Slowing down of heart rate, Visual disturbances, Dizziness, CNS disturbances, Nausea, Vomiting, Diarrhea, Skin rashes

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Digoxin Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Digoxin as it can exaggerate side effects of dizziness and CNS disturbances, all of which could affect your concentration and ability to drive.

Pregnancy Not Safe

Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may outweigh the risk. Please consult your doctor before using it.

Lactation Safe If Prescribed

Digoxin is excreted into breast milk in small amounts but no adverse effects on the nursing infant have been reported. Please consult your doctor before using it.

Driving Not advisable

Digoxin may cause CNS disturbances and vision problems, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Kidney Use With Care

Digoxin should be used with caution in patients with severe kidney disease because renal excretion is the main route of elimination. Dose adjustment of Digoxin may be needed. Please consult your doctor before using it.

Liver Safe If Prescribed

Digoxin metabolism is not affected in hepatic impairment. Please consult your doctor before using it.