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Diphenoxylate is commonly used in the treatment of diarrhea
Diphenoxylate affects the smooth muscles of the intestinal tract where it causes slowing down of the intestinal motility and reduces the excessive GI propulsion.
Headache, Drowsiness, Dizziness, Restlessness, Euphoria, Depression, Numbness of the extremities, Hypersensitivity reaction, Gum swelling
It is not advisable to take alcohol with Diphenoxylate as it would potentiate effects of CNS depressants
Diphenoxylate may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable even with the risk. Please consult your doctor.
Diphenoxylate is shown to be excreted in breast milk. It is not advisable for women to breastfeed while consuming Diphenoxylate because of its potential adverse effects on infants.
Do not drive unless you are feeling well. Diphenoxylate may cause side effects such as dizziness, drowsiness or numbness, all of which could affect the ability to concentrate and drive.
Diphenoxylate is safe to be used in patients with kidney disease and no dosage adjustment required. However, please consult your doctor.
Diphenoxylate should be used with caution in patients with liver disease. Dose adjustment of Diphenoxylate may be needed. Please consult your doctor.
