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Eltrombopag is commonly used to treat chronic idiopathic thrombocytopenia, idiopathic thrombocytopenic purpura, chronic hepatitis c infection and aplastic anemia.
Eltrombopag is a haemostatic agent which exerts its action on the pathway regulating megakaryopoiesis and platelet production. Eltrombopag will activate thrombopoietin (TPO) receptor, initiating marrow progenitor cells proliferation and differentiation and thus increasing the platelet production.
Upper respiratory tract infection, Cough, Fever, Anaemia, Decreased appetite, Paraesthesia, Dry eye, Vision blurred, Eye pain, Ear pain, Vertigo, Cough, Hot flush, Nausea, Diarrhea, Rash, Alopecia, Hyperhidrosis, Petechiae, Musculoskeletal pain
Even though there is insufficient data on drug interactions between alcohol and Eltrombopag. However, generally drinking alcoholic beverages should be kept to a minimum or avoided completely. Please consult your doctor before using it.
Eltrombopag may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may outweigh the risk. Please consult your doctor before using it.
Eltrombopag is excreted into the breastmilk of animal studies but its excretion into human breast milk is largely unknown. The decision whether to discontinue breast-feeding or to withhold from Eltrombopag therapy is to be after consulting with your doctor.
Eltrombopag may cause side effects such as blurring of vision and vertigo all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.
Eltrombopag should be used with caution and close monitoring of their renal function in patients with mild kidney disease. Dose adjustment of Eltrombopag may be needed. Please consult your doctor before using it. Use of Eltrombopag in patients with moderate to severe kidney disease has not been studied adequately.
Eltrombopag should be used with caution in patients with mild to moderate liver disease. Dose adjustment of Eltrombopag may be needed. Please consult your doctor before using it. Use of Eltrombopag in patients with severe liver disease is contraindicated.
