Emtricitabine

Information About Emtricitabine

Uses of Emtricitabine

Emtricitabine is commonly used to treat hiv infection.

How Emtricitabine Works

Emtricitabine is a synthetic nucleoside analogue of cytidine, undergoes molecular changes to become active. It then gets incorporated into viral DNA which results in chain termination and stopping the viral replication.

Side Effects of Emtricitabine

Diarrhea, Headache, Elevated creatine kinase, Nausea, Increased number of white blood cells, Allergic reaction, Insomnia, Abdominal pain, Dyspepsia, Rash, Anemia, Skin discolouration

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Emtricitabine Related Warnings

Alcohol Not Advisable

Rare cases of Osteonecrosis have been reported in patients with advanced HIV disease and long- term antiretroviral therapy. However, it is due to several factors including chronic alcohol consumption. Drug interactions are still inconclusive. Please consult your doctor before using it.

Pregnancy Maybe Safe

Emtricitabine may be unsafe to use during pregnancy. Animal studies have not shown adverse effects on the fetus but there are limited human studies. Please consult your doctor before using it.

Lactation Not Advisable

Dolutegravir is excreted in breast milk but there are limited studies regarding its effect on feeding baby. It is also recommended that HIV- positive mothers do not breastfeed their children regardless of circumstances to avoid transmission of HIV.

Driving Generally Safe

Emtricitabine may cause side effects of headaches, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Kidney Use With Care

Emtricitabine should be used with caution in patients with severe kidney disease. Dose adjustment of Emtricitabine may be needed. Please consult your doctor before using it.

Liver Use With Care

Emtricitabine should be used with caution in patients with liver disease. Dose adjustment of Emtricitabine may be needed. Please consult your doctor before using it.