Eperisone

Information About Eperisone

Uses of Eperisone

Eperisone is commonly used to treat arthritis, low back pain or spastic paralysis caused by various cerebrovascular disorders, spastic spinal paralysis, cervical spondylosis, surgical trauma sequelae or trauma sequelae.

How Eperisone Works

Eperisone is a centrally-acting agent that relaxes skeletal muscles by relaxing muscle rigidity and suppression of spinal reflexes. It also reduces the sensitivity of muscle spindle via alpha�-motor neurons in addition to causing vasodilation, altering blood flow.

Side Effects of Eperisone

Rash, Sleepiness, Insomnia, Headache, Numbness in extremities, Nausea, Vomiting, Reduced appetite, Diarrhea, Constipation, Thirst, Lightheadedness, Fatigue, Hot flushes

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Eperisone Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Eperisone as there may be drug interactions when they are taken at the same time.

Pregnancy Not Safe

Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may outweigh the risk. Please consult your doctor before using it.

Lactation Limited Data

There's excretion of Entecavir into the breastmilk of mammals but there is limited human data and its effect to a breastfed baby is still largely unknown. The benefits from use in pregnant women may outweigh the risk. Please consult your doctor before using it.

Driving Generally Safe

Eperisone may cause side effects such as dizziness, headaches, nausea or fatigue, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Excretion of Eperisone is not affected significantly in patients with kidney disease. However, dose adjustment of Eperisone may be needed. Please consult your doctor before using it.

Liver Limited Data

Eperisone should be used with caution in patients with liver disease. Dose adjustment of Eperisone may be needed. Please consult your doctor before using it.