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Eplerenone is commonly used to treat heart failure and hypertension.
The pathway of renin-angiotensin-aldosterone-system (RAAS) causes renal reabsorption of sodium, vascular remodelling, water retention and the endothelium. Eplerenone inhibits RAAS involving the kidney, digestive system, cardiovascular tissue and brain tissue.
Cough, Difficulty sleeping (insomnia), Dizziness, Syncope, Headache, Left ventricular failure, Atrial fibrillation, Decrease in blood pressure (hypotension), Diarrhea, Nausea, Constipation, Vomiting, Rash, Muscle Spasm, Kidney dysfunction
It is unsafe to consume alcohol with Eplerenone as it may aggravate lowering of your blood pressure. With hypotension, you may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Eplerenone may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. Please consult your doctor before using it.
Eplerenone is excreted into the breastmilk of mammals in animal studies but is largely unknown in human studies. Due to its potential adverse effect on feeding infant, the decision to continue Eplerenone or withhold breastfeeding is to be done after consultation with your doctor.
Eplerenone may cause side effects such as dizziness, headaches or nausea, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.
Eplerenone should be used with caution in patients with mild to moderate kidney disease. Dose adjustment of Eplerenone may be needed. Please consult your doctor before using it. Use of Eplerenone is not recommended in patients with severe kidney disease.
Eplerenone should be used with caution in patients with mild-to-moderate liver disease. Dose adjustment of Eplerenone may be needed. Please consult your doctor before using it. Use of Eplerenone is not recommended in patients with severe kidney disease.
