Ezetimibe

Information About Ezetimibe

Uses of Ezetimibe

Ezetimibe is commonly used to treat patients with high cholesterol levels.

How Ezetimibe Works

Ezetimibe inhibits the absorption of cholesterol via the sterol transporter, NPC1L1

Side Effects of Ezetimibe

Headache, Myalgia, Abdominal pain, Diarrhea, Fatigue, Chest pain, Rash

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ezetimibe Related Warnings

Alcohol Safe

It is safe to consume Ezetimibe with alcohol.

Pregnancy Not Safe

Ezetimibe may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable even with the risk. Please consult your doctor.

Lactation Limited Data

No academic reports explaining the use of Ezetimibe for breastfeeding mothers have been located. However, if ezetimibe is taken by breastfeeding mothers, the nursing infant should be closely monitored for any adverse reactions.

Driving Generally Safe

Ezetimibe usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

Ezetimibe should be used with caution in patients with severe kidney disease. Dose adjustment of Ezetimibe may be needed. Please consult your doctor.

Liver Limited Data

Ezetimibe is not recommended in patients with moderate and severe liver disease; Child Pugh Score > 7. Please consult your doctor.