Fluticasone Propionate Nasal

Information About Fluticasone Propionate Nasal

Uses of Fluticasone Propionate Nasal

Fluticasone propionate nasal is commonly used in the treatment of nasal polyps and allergic rhinitis.

How Fluticasone Propionate Nasal Works

Fluticasone Propionate Nasal is an anti-inflammatory, antipruritic, and vasoconstrictive. It inhibits the late phase of allergic reactions which include decreasing the density of mast cells, decreasing chemotaxis and activation of eosinophils, reducing the production of cytokine and inhibiting arachidonic acid metabolism.

Side Effects of Fluticasone Propionate Nasal

Weight gain, Cushingoid features, Hyperglycemia, Hypertension, Cataract, Osteoporosis, Glaucoma, Pruritis, Skin thinning, Telangiectasia

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Fluticasone Propionate Nasal Related Warnings

Alcohol Safe

It could be safe to consume alcohol with Fluticasone Propionate Nasal, but it is recommended to limit the amount as the interactions are still unknown.

Pregnancy Not Safe

Animal studies have demonstrated that it can cause developmental abnormalities to the fetus and there are inadequate human studies, however, the potential benefits may allow the usage of Fluticasone Propionate Nasal in pregnant women despite the risks. It is also recommended to only use minimum quantity for a minimum duration of the treatment.

Lactation Limited Data

It is unknown whether Fluticasone Propionate Nasal or its metabolites is excreted in human breast milk. Animal studies reported that there was evidence of Fluticasone Propionate Nasal in the rat's milk following subcutaneous administration. It is recommended to avoid using Fluticasone Propionate Nasal during breastfeeding unless the benefits to the mother outweigh the benefits of breastfeeding to the child.

Driving Generally Safe

Fluticasone Propionate Nasal usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

In patients with renal impairment, the metabolism and elimination of this drug might be delayed in systemic absorption and thus, increases the risk of systemic toxicity. Therefore, to achieve clinical benefit, only the minimum quantity should be used for the shortest duration of treatment.

Liver Limited Data

In patients with liver impairment, the metabolism and elimination of Fluticasone Propionate Nasal might be delayed in systemic absorption and thus, increases the risk of systemic toxicity. Therefore, to achieve clinical benefit, only the minimum quantity should be used for the shortest duration of treatment.