Glimepiride+Metformin

Information About Glimepiride+Metformin

Uses of Glimepiride+Metformin

Glimepiride+Metformin is used in treating Type 2 diabetes mellitus especially for patients that could not achieve sufficient control of blood sugar level with glimepiride or metformin alone.

How Glimepiride+Metformin Works

Glimepiride acts on the pancreas which helps produce more insulin. Metformin helps reduce glucose production by the liver, which also helps body to make better use of insulin and delay the glucose absorption in intestines.

Side Effects of Glimepiride+Metformin

Nausea, Vomitting, Abdominal Pain, Metallic Taste In The Mouth.

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Glimepiride+Metformin Related Warnings

Alcohol Not Advisable

Alcohol may affect blood glucose levels in patients with diabetes. Glimepiride+Metformin might also increase the risk of diabetes ketoacidosis but this mostly applies to patients who abuse alcohol. Generally, it is not advisable to have alcohol with Glimepiride+Metformin.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities and prolonged severe hypoglycaemia has been reported in newborns to mother receiving Glimepiride+Metformin at time of delivery. Glimepiride+Metformin is not recommended during pregnancy. Consult your doctor before using this Glimepiride+Metformin.

Lactation Not Advisable

There are no data on the effect of Glimepiride+Metformin upon breastfed babies. Thus, Glimepiride+Metformin is contraindicated during breastfeeding. Please consult your doctor.

Driving Generally Safe

Glimepiride+Metformin should not affect alertness or driving ability.

Kidney High Risk

Dose adjustment may be needed in patients with moderate kidney impairment. It is contraindicated in patients with severe kidney impairment. Please consult your doctor.

Liver Use With Care

Dose adjustment may be needed in patients with moderate liver impairment. It is contraindicated in patients with severe liver impairment. Please consult your doctor.