Granisetron

Information About Granisetron

Uses of Granisetron

Granisetron is commonly used to treat nausea, vomiting

How Granisetron Works

Granisetron is a potent antiemetic. It treats nausea and vomiting by acting as a highly selective antagonist of 5-hydroxytryptamine (5-HT3) receptors.

Side Effects of Granisetron

Headache, Difficulty sleeping (insomnia), Constipation, Elevated liver function test, Diarrhea, Rash

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Granisetron Related Warnings

Alcohol Safe

It is safe to consume alcohol with Granisetron as there is no known interaction between them.

Pregnancy Not Safe

Granisetron may be unsafe to use during pregnancy. Animal studies have shown no adverse effects on the fetus and there are limited human studies regarding the adverse effect. It can be used if the benefits outweigh the risks. Please consult your doctor.

Lactation Limited Data

There is no information about the presence of Granisetron in human milk. Therefore, it is not recommended to take Granisetron whilst lactating.

Driving Generally Safe

Granisetron has no influence on the general attention and ability to drive.

Kidney Safe If Prescribed

Dose adjustment of Granisetron is not needed in kidney disease.

Liver Limited Data

Although dosage adjustment is not needed in patients with liver disease, Granisetron should be used with caution on the basis of the pharmacokinetics.