Isosorbide Dinitrate

Information About Isosorbide Dinitrate

Uses of Isosorbide Dinitrate

Isosorbide dinitrate is commonly used to treat anal fissure, angina heart related chest pain, coronary artery disease, heart failure, hypertensive emergency

How Isosorbide Dinitrate Works

Isosorbide Dinitrate works by relaxing the vascular smooth muscles hence decreases the ventricular pressure and resistance of the artery.

Side Effects of Isosorbide Dinitrate

Dizziness, Headache, Syncope, Rapid heartbeat, Heartburn, Nausea, Vomit

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Isosorbide Dinitrate Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Isosorbide Dinitrate. Taking Isosorbide Dinitrate with alcohol may have additive effects on vasodilation. Side effects of alcohol such as dizziness, headache and rapid heartbeat may worsen with alcohol intake.

Pregnancy Not Safe

Animal studies have shown adverse effects on the fetus, however, there are no adequate and well-controlled human studies. However, if benefit of use justifies risk, usage of Isosorbide Dinitrate may be considered. Please consult your doctor.

Lactation Limited Data

There are limited data on usage of Isosorbide Dinitrate during lactation. Usage is therefore suggested if benefit justifies the risk.

Driving Not advisable

(Do not drive unless you are feeling well.) Isosorbide Dinitrate may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney Use With Care

Isosorbide Dinitrate should be used with caution in patients with severe kidney disease. Dose adjustment of Isosorbide Dinitrate may be needed. Please consult your doctor.

Liver Limited Data

Isosorbide Dinitrate should be used with caution in patients with liver disease. Dose adjustment of Isosorbide Dinitrate may be needed. Please consult your doctor.