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Methyldopa is commonly used to treat hypertension
Methyldopa works by stimulating the central alpha-adrenergic receptor which results in reduce sympathetic tone.
Drowsiness, Headache, Low blood pressure, Weakness, Fatigue, Disturbed sleep, Impotence, Nausea, Vomiting
There is no clear contraindication on the consumption of alcohol when taking Methyldopa.
Methyldopa crosses placenta but according to human pregnancy data, it is safe to be used as there were no fetal harm or toxicity reported.
The metabolites of Methyldopa been detected in human breastmilk and thus it should be used with caution during breastfeeding only if the benefits outweigh the risks.
It is not advisable to drive when under Methyldopa treatment due to its potential side effects such as fatigue, headache and dizziness which can affect the ability to concentrate and drive.
Dosage adjustment may be needed for patients with renal impairment with lower doses.
Methyldopa should be used with caution and close monitoring is advisable for patients with hepatic impairment. It is contraindicated in those with active liver disease.
