Nifedipine

Information About Nifedipine

Uses of Nifedipine

Nifedipine is commonly used in the treatment of anal fissure, angina heart-related chest pain, arrhythmias, hypertensive emergency, subarachnoid haemorrhage.

How Nifedipine Works

Nifedipine is a calcium channel blocker that inhibits Calcium ions from entering the cardiac and smooth muscles causing the peripheral and coronary vasodilation. This leads to reduced afterload and peripheral resistance which helps to relieve the workload of the heart.

Side Effects of Nifedipine

Dizziness, Flushing, Headache, Low blood pressure, Peripheral oedema, Tachycardia, Palpitations, Nausea, Constipation, Syncope, Vertigo, Visual disturbance

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Nifedipine Related Warnings

Alcohol Not Advisable

Alcohol will inhibit the metabolism of Nifedipine, which will further accentuate the side effects of Nifedipine.

Pregnancy Not Safe

Nifedipine should not be used during pregnancy unless clinical condition requires its usage urgently.

Lactation Not Advisable

Nifedipine is not safe for breastfeeding as it may be excreted in breast milk. It is only proven in animal studies and it shows impairment in the development of baby animals. This risk cannot be excluded in humans thus it isn't safe

Driving Not advisable

Do not drive unless you are feeling well. Nifedipine may cause side effects such as headache, vertigo or visual disturbances especially at the start of treatment, all of which could affect the ability to concentrate and drive.

Kidney Safe If Prescribed

Nifedipine is safe to be used in patients with kidney disease.

Liver Use With Care

Nifedipine should be used with caution in patients with liver disorder. Dose adjustment of Nifedipine may be needed. Please consult your doctor.