Osimertinib

Information About Osimertinib

Uses of Osimertinib

Osimertinib is commonly used to treat locally advanced or metastatic non-small cell lung carcinoma.

How Osimertinib Works

Osimertinib is a Tyrosine Kinase Inhibitor. It is an irreversible inhibitor of Epidermal Growth Factor Receptors (EGFRs).

Side Effects of Osimertinib

Diarrhea, Rash, Dry skin, Pruritus, Nail changes, Stomatitis, Decreased platelet count, Decreased white blood cells, Interstitial lung disease

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Osimertinib Related Warnings

Alcohol Safe

Consuming alcohol in moderation with Osimertinib does not seem to affect the pharmacodynamics of Osimertinib. However, please consult your doctor before using it.

Pregnancy Limited Data

Osimertinib may be unsafe to use during pregnancy. Both animal studies and human studies have limited data on the adverse effects on the fetus. . It is not recommended for use in pregnant women. Please consult your doctor before using it.

Lactation Not Advisable

Osimertinib is probably excreted into human breast milk. However, there is limited data on the adverse effect of Osimertinib to the feeding baby. Please consult your doctor before using it.

Driving Generally Safe

Osimertinib cause minimal to no side effects which could affect your ability to concentrate and drive.

Kidney Use With Care

Osimertinib should be used with caution in patients with kidney disease. Dose adjustment of Osimertinib may be needed. Please consult your doctor before using it.

Liver Use With Care

Osimertinib should be used with caution in patients with mild to moderate liver disease. Dose adjustment of Osimertinib may be needed. Please consult your doctor before using it. Use of Osimertinib is not recommended in patients with severe liver disease.