Pentoxifylline

Information About Pentoxifylline

Uses of Pentoxifylline

Pentoxifylline is commonly used to treat peripheral vascular disease.

How Pentoxifylline Works

Pentoxifylline helps to improve microcirculation and peripheral tissue oxygenation by increasing blood flow. This is because it decreases blood viscosity, increases leukocyte deformability and erythrocyte flexibility, and decreases neutrophil activation.

Side Effects of Pentoxifylline

Anaphylactic reaction, Chest pain, Transient hypotension, Headache, Dizziness, Tremor, Nervousness, Drowsiness, Flushing, Nausea, Vomiting, Epigastric discomfort, Abdominal distention, Constipation, Diarrhea, Bronchospasm, Blurred vision, Pruritus

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Pentoxifylline Related Warnings

Alcohol Safe

There's no known drug/alcohol interactions in Pentoxifylline. However, please consult your doctor before using it.

Pregnancy Not Safe

Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Lactation Limited Data

Pentoxifylline is excreted into breast milk in trace quantities. However, its potential adverse effect on the feeding baby is largely unknown. Please consult your doctor before using it.

Driving Generally Safe

Pentoxifylline cause minimal to no side effects which could affect your ability to concentrate and drive.

Kidney Use With Care

Pentoxifylline should be used with caution in patients with kidney disease. Dose adjustment of Pentoxifylline may be needed. Please consult your doctor before using it.

Liver Limited Data

Pentoxifylline should be used with caution in patients with liver disease. Dose adjustment of Pentoxifylline may be needed. Please consult your doctor before using it.