Pimecrolimus

Information About Pimecrolimus

Uses of Pimecrolimus

Pimecrolimus is commonly used to treat atopic dermatitis

How Pimecrolimus Works

Pimecrolimus is an immunosuppressant which works by blocking the activation and proliferation of T-cells which in turn prevent the release of inflammatory chemicals and mediators from the mast cells.

Side Effects of Pimecrolimus

Burning sensation, Redness of the skin, Skin infection, Swollen lymph nodes, Headache, Cough, Rhinitis, Upper respiratory tract infection, Fever

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Pimecrolimus Related Warnings

Alcohol Not Advisable

It is not advisable to consume or take alcohol when on Pimecrolimus as the latter may exacerbate the skin side effects of alcohol.

Pregnancy Not Safe

Animal reproductive studies have shown foetal toxicity when only given orally. There is no embryological or fetal toxicity when it is applied to the skin. Pimecrolimus should be used with caution during pregnancy considering the risks and benefits.

Lactation Limited Data

It is not known whether Pimecrolimus is excreted into human breastmilk or not. Due to its potential toxicity, Pilocarpine is not advisable to be used during breastfeeding.

Driving Generally Safe

Pimecrolimus is generally safe to be used before driving as the side effects profile does not suggest any disruption on the concentration or ability to drive.

Kidney Safe If Prescribed

No dosage adjustment is needed for patients with renal impairment as indicated by the manufacturer labelling.

Liver Limited Data

There is no dosage adjustment needed for patients with hepatic impairment according to the manufacturer labelling.