Prazosin

Information About Prazosin

Uses of Prazosin

Prazosin is commonly used to treat hypertension, heart failure, benign prostatic hyperplasia, and raynaud's syndrome.

How Prazosin Works

Prazosin decreases total peripheral resistance and blood pressure by competitively inhibits postsynaptic alpha1-adrenoreceptors in vascular smooth muscles.

Side Effects of Prazosin

Abdominal pain, Constipation, Vomiting, Insomnia, Edema, Blurred vision, Dyspnoea, Syncope, Hypotension

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Prazosin Related Warnings

Alcohol Not Advisable

Consuming alcohol while taking Prazosin may lower your blood pressure which can lead to loss of consciousness. Therefore this is not recommended.

Pregnancy Not Safe

Prazosin in animal studies had not shown teratogenic effects, however, it is safety has yet to be established in humans. This medication should only be used in pregnancy if the benefits outweigh the risks.

Lactation Limited Data

Prazosin may be excreted in breastmilk in a small amount. This medication should be used with caution in breastfeeding women.

Driving Not advisable

As an antihypertensive agent, Prazosin carries the risk of postural hypotension which may impair the ability to drive and operating machines. Patients should be thought how to recognize, avoid and manage this problem. Advised to drive only if they are feeling well.

Kidney Safe If Prescribed

Prazosin is safe to be used in patients with kidney impairment

Liver Limited Data

No data available on the usage of Prazosin in patients with liver impairment