Ramipril

Information About Ramipril

Uses of Ramipril

Ramipril is commonly used to treat hypertension, heart attack, and heart failure

How Ramipril Works

Ramipril is an ACE inhibitor. It competitively inhibits ACE from converting angiotensin I to angiotensin II which cause an increase in plasma renin activity and reduction of aldosterone.

Side Effects of Ramipril

Cough, Syncope, Dyspnoea, Vomiting, Hypotension, Headache, Angioedema, Dizziness

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ramipril Related Warnings

Alcohol Not Advisable

It is not recommended to consume alcohol while taking this medication as it may potentiate Ramipril side effects of hypotension.

Pregnancy Not Safe

The ACE inhibitor has a small risk of teratogenicity if exposed during first trimester of pregnancy and exhibit possible effect of fetotoxicity during the second trimester onwards. Therefore Ramipril is contraindicated during pregnancy unless the benefits clearly outweigh the risks.

Lactation Limited Data

Limited data is available on the safety of Ramipril in breastfeeding. Therefore Ramipril is not recommended to be given to breastfeeding mothers.

Driving Not advisable

Consumption of Ramipril may impair the ability to drive and operating machines. Only drive if you are feeling well.

Kidney Use With Care

Dose adjustment of Ramipril is needed in a patient with kidney impairment.

Liver Limited Data

Dose adjustment is needed in a patient with liver failure and close monitoring should be done in these patients.