Ritonavir

Information About Ritonavir

Uses of Ritonavir

Ritonavir is commonly used to treat hiv infection

How Ritonavir Works

Ritonavir is an HIV protease inhibitor that will disrupt the production of proteins and enzymes of the HIV

Side Effects of Ritonavir

Gut disturbances, Taste disturbances, Headache, Perioral/Limbs numbness, Insomnia, Skin rash, Weight loss, Immune reconstitution syndrome, Increased triglyceride and cholesterol level, Hyperglycaemia, Pancreatitis, Liver dysfunction

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Ritonavir Related Warnings

Alcohol Not Advisable

Alcohol may accentuate the liver damage caused by Ritonavir. Thus, it is not advisable to consume alcohol and Ritonavir concomitantly.

Pregnancy Maybe Safe

Animal studies have shown reproductive toxicities but human studies have not shown any reproductive toxicities. Thus, Ritonavir can be used during pregnancy if needed.

Lactation Not Advisable

Excretion of Ritonavir is found in human breast milk but there is no information on the effects of Ritonavir on breastfed babies. An HIV-infected woman should not breastfeed to prevent HIV transmission, developing viral resistance and serious side effects onto the breastfed babies. Please consult your doctor.

Driving Generally Safe

Ritonavir usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Safe If Prescribed

Ritonavir is safe to be used in patients with kidney impairment.

Liver Use With Care

No dose adjustment needed for patients with mild to moderate liver impairment. However, Ritonavir is contraindicated in patients with severe liver impairment. Please consult your doctor.