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Roflumilast is commonly used to treat chronic obstructive pulmonary disease (copd)
Roflumilast is a phosphodiesterase-4 inhibitor which has anti-inflammatory and anti-modulatory effects in the lungs.
Weight loss, Anxiety, Insomnia, Abdominal pain, Nausea, Diarrhea, Decreased appetite, Back pain, Headache, Dizziness
There is no known interaction between alcohol and Roflumilast when consumed concomitantly. However, alcohol is not advisable for a patient with COPD as it will worsen the condition.
Animal studies have shown reproductive toxicities but there are limited data on the use of Roflumilast in pregnant women. Thus, it is not advisable to be used during pregnancy.
Excretion of Roflumilast has been found in animal milk but it is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding as risks cannot be excluded.
Roflumilast usually does not affect the ability to drive. Do not drive unless you are feeling well.
Roflumilast is safe to be used in patients with kidney impairment.
Dose adjustment is needed in patients with mild liver impairment. Roflumilast is contraindicated in patients with moderate to severe liver impairment.
