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Saxagliptin is commonly used to treat type 2 diabetes mellitus
Saxagliptin is a dipeptidyl peptidase-4 inhibitor which is able to increase the level of glucagon-like peptide 1 (GLP-1) that is responsible for glucagon production inhibition and increased insulin production.
Headache, Fatigue, Dizziness, Heartburn, Peripheral oedema, Muscle/Joint ache, Hypoglycaemia, Hypertriglyceridaemia, Erectile dysfunction, Allergic reactions, Pancreatitis
The interaction of alcohol and saxagliptin have not been studied specifically. Thus, it is not advisable to consume alcohol with Saxagliptin as risks cannot be excluded.
Animal studies have shown reproductive toxicities at high doses but there are no data on the use of Saxagliptin in pregnant women. Thus, it is not advisable to be used unless clearly indicated. Please consult your doctor.
Excretion of Saxagliptin has been found in animal milk but it is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.
Saxagliptin usually does not affect the ability to drive. Do not drive unless you are feeling well.
Dose adjustment is needed in patients with moderate to severe kidney impairment. Saxagliptin is contraindicated in patients with end-stage kidney disease on hemodialysis.
Caution use has to be practised in patients with moderate liver impairment. Saxagliptin is contraindicated in patients with severe liver impairment.