Sulfasalazine

Information About Sulfasalazine

Uses of Sulfasalazine

Sulfasalazine is commonly used to treat crohn's disease, rheumatoid arthritis and ulcerative colitis.

How Sulfasalazine Works

The anti-inflammatory property of Sulfasalazine has not been clearly understood

Side Effects of Sulfasalazine

Headache, Decreased appetite, Nausea, Vomiting, Abdominal discomfort, Photosensitivity, Yellow-orange staining of the urine and other bodily fluids, Hair loss, Allergic reactions

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Sulfasalazine Related Warnings

Alcohol Not Advisable

There is no known interaction between alcohol and Sulfasalazine when used concomitantly. However, alcohol may worsen the damage upon your liver as Sulfasalazine can affect your liver as well.

Pregnancy Maybe Safe

Animal studies and human studies have not shown reproductive toxicities. However, Sulfasalazine may inhibit the absorption and metabolism of folic acid which is needed for foetal growth. Thus, Sulfasalazine is not advisable to be used during pregnancy unless necessary because the possibility of harm cannot be completely ruled out. Please consult your doctor.

Lactation Not Advisable

Excretion of Sulfasalazine has been found in human breastmilk and has effects on breastfed babies. Thus, it is not advisable to be used during breastfeeding.

Driving Generally Safe

Sulfasalazine usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

Dose adjustment and caution use have to be practised in patients with kidney impairment.

Liver Use With Care

Sulfasalazine is contraindicated in patients with liver impairment.