Tacrolimus

Information About Tacrolimus

Uses of Tacrolimus

Tacrolimus is commonly used in the treatment of atopic dermatitis, bone marrow transplantation, nephrotic syndrome, prevention of organ rejection in transplant patients, rheumatoid arthritis, and uveitis

How Tacrolimus Works

Tacrolimus is a Dermatological medication and also Immunosuppressants. Tacrolimus has strong macrolides property of Tacrolimus which is able to inhibit T-cell activation and T-helper-cell dependent B-cell proliferation.

Side Effects of Tacrolimus

Headache, Tremor, Nausea, Vomiting, Infection, Lethargy, Urticaria

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Tacrolimus Related Warnings

Alcohol Not Advisable

It is unsafe to consume alcohol with Tacrolimus. It may cause a visual and neurological effect if consumed with alcohol.

Pregnancy Not Safe

Tacrolimus may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable even with the risk. Please consult your doctor.

Lactation Not Advisable

Tacrolimus is probably unsafe to use during lactation as some amount of Tacrolimus is excreted in breast milk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Tacrolimus may cause side effects such as visual and neurological disturbances, all of which could affect the ability to concentrate and drive.

Kidney High Risk

Tacrolimus is not safe to be used in patients with kidney disease. Dose adjustment of Tacrolimus may not be required. Please consult your doctor.

Liver Use With Care

Tacrolimus should be used with caution in patients with liver disease. Dose adjustment of Tacrolimus may be needed. Please consult your doctor.