Thiamine

Information About Thiamine

Uses of Thiamine

Vitamin B1/Thiamine is usually given parenterally to prevent Wernicke-Korsakoff Syndrome.

How Thiamine Works

Thiamine is an essential enzyme that form thiamine pyrophosphate when combines with ATP and involves in the carbohydrate metabolism

Side Effects of Thiamine

Warm sensation, Tingling, Pruritus and urticaria, Pain, Respiratory distress, Angioedema, Gastrointestinal bleeding, Transient vasodilation and hypotension, Vascular collapse, Anaphylactic shock

Authorship

Written By

Dr Sri Viknarajan

MD (Universiti Hasanuddin, Indonesia)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Thiamine Related Warnings

Alcohol Safe

There is no known harmful interaction between Vitamin B1/Thiamine and alcohol and in fact, alcoholic patients were given vitamin B1 intravenously because they may have reduced absorption of vitamin B1.

Pregnancy Safe If Prescribed

Vitamin B1/Thiamine may be safe to use during pregnancy. Controlled studies in women fail to demonstrate a risk to the foetus in the 1st trimester (and there is no evidence of a risk in later trimesters), and the possibility of foetal harm remains unknown.

Lactation Safe If Prescribed

Vitamin B1/ Thiamine is safe to use during lactation. Limited human data suggests that Vitamin B1/Thiamine does not represent a significant risk to the baby and in fact, the requirements for it are increased during lactation period.

Driving Generally Safe

Vitamin B1/Thiamine has no effect on the ability to drive.

Kidney Safe If Prescribed

Studies found that high doses of Vitamin B1/Thiamine may actually reverse the onset of early diabetic kidney disease.

Liver Safe If Prescribed

Vitamin B1/Thiamine is given to alcoholic patients to prevent the development of Wernicke encephalopathy.