Tranexamic Acid

Information About Tranexamic Acid

Uses of Tranexamic Acid

Tranexamic acid is commonly used to stop bleeding.

How Tranexamic Acid Works

Tranexamic acid acts by blocking the binding of plasminogen and plasmin to fibrin thus inhibiting fibrinolysis. As a result, the dissolution of the hemostatic plug is prevented.

Side Effects of Tranexamic Acid

Visual disturbance, Thromboembolic events, Seizure, Abdominal pain and discomfort, Nausea, Vomiting, Diarrhea, Headache, Migraine, Muscle pain and cramps

Authorship

Written By

Dr Mohd Ramzdhan Bin Mohd Masdar

MD (Crimea State Medical University)

Reviewed By

Dr Nur Syuhada binti Zulkifli

MD, Universiti Kebangsaan Malaysia (UKM)

Tranexamic Acid Related Warnings

Alcohol Safe

Consumption of alcohol while on Tranexamic Acid is relatively safe however, please consult with your doctor to discuss for further drug interactions that might occur.

Pregnancy Maybe Safe

Animal studies have revealed no evidence of harm to the fetus, however, inadequate studies in pregnant women/animal studies have shown an adverse effect. Nevertheless, the use of Tranexamic Acid with caution in pregnancy should be cautious as it crosses the placenta.

Lactation Limited Data

Tranexamic acid is excreted into breast milk, however, an antifibrinolytic effect in the infant is unlikely. Please consult your doctor before nursing your baby.

Driving Generally Safe

Tranexamic acid usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Use With Care

It has to be used with cautious because of slower removal of the medicine from the body. Also, blood levels are increased in patients with renal insufficiency and it should not be used in patients with severe renal impairment.

Liver Limited Data

Tranexamic Acid is safe to be used in a cirrhotic patient suffering from upper gastrointestinal bleeding